359: Enactment of the rank of the Eparch of the City.
641: Loss of Egypt which was Constantinople's main supplier of grain.
Middle of the 7th c: End of free food distribution.
9th - 12th c.: Constant population growth and development of commerce in the Mediterranean.
1204: Conquest of Constantinople by the army of the Fourth Crusade.
1261: Recapture of Constantinople by the Byzantines.
14th - 15th c. Significant dependence on the merchants of the Italian states. The population decrease meant that Constantinople was depended to a great extent on the agricultural production inside the walls.